PLAID is a multimodal generative model that simultaneously generates protein 1D sequence and 3D structure, by learning the latent space of protein folding models. The awarding of the 2024 Nobel Prize to AlphaFold2 marks an important moment of recognition for the of AI role in biology. What comes next after protein folding? In PLAID, we…

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Training Diffusion Models with Reinforcement Learning We deployed 100 reinforcement learning (RL)-controlled cars into rush-hour highway traffic to smooth congestion and reduce fuel consumption for everyone. Our goal is to tackle “stop-and-go” waves, those frustrating slowdowns and speedups that usually have no clear cause but lead to congestion and significant energy waste. To train efficient…

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Cloudflare has announced its first-ever mass layoff, cutting approximately 1,100 employees — 20% of its workforce — as it reported record quarterly revenue of $639.8 million, a 34% year-over-year increase. Co-founder and CEO Matthew Prince and co-founder and president Michelle Zatlyn framed the cuts not as cost reduction but as a structural response to AI-driven productivity gains. Prince said…

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Oracle’s abrupt termination of an estimated 20,000 to 30,000 employees via email on March 31 has sparked significant employee pushback over what many regarded as inadequate severance. The company offered four weeks of base pay plus one additional week per year of service, capped at 26 weeks, but crucially did not accelerate unvested stock grants — meaning…

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Insider Brief Modicus Prime has raised an additional $4.5 million led by Frist Cressey Ventures, bringing total funding to $8 million, to expand its Trustworthy AI Compliance Software that helps pharmaceutical companies deploy audit-ready AI across regulated GxP environments globally. The platform integrates with existing pharmaceutical tech stacks and quality management systems, serving as a…

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AI Library, an outcome-based software delivery startup founded in 2023 by Arani Chaudhuri, has raised $560,000 in pre-seed funding at a $7.5 million valuation cap to accelerate its AI agent-driven approach to enterprise software deployment. The company’s platform automates the software delivery lifecycle using AI agents with human oversight, targeting enterprise functions including finance, operations,…

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Paris-based AI real estate startup Davis has raised €4.6 million in a pre-seed round led by Heartcore Capital and Balderton Capital, with participation from Yellow, Evantic, and Entrepreneurs First, alongside angels from the founding teams of Hugging Face, Black Forest Labs, and Supabase. Founded in 2025 by CEO Mehdi Rais and Amine Chraibi, Davis combines…

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Swiss startup Moonlight AI has closed a $3.3 million seed round co-led by Lotus One Investment, VP Venture Partners, and MEDIN Fund, with participation from N&V Capital and QAI Ventures, to advance AI-powered image analysis for clinical oncology diagnostics. Founded by CEO Christian Ruiz, CTO Nicole Romano, and CMO Stefan Habringer, the company uses computer…

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Insider Brief Tessera Labs has raised $60 million in an oversubscribed round led by Andreessen Horowitz, with Foundation Capital and others participating, to accelerate its AI-native platform for enterprise ERP transformation, with a16z partner Seema Amble joining the board. The company’s vendor-agnostic, multi-agent platform is pre-trained on thousands of organizational landscapes and compresses transformation timelines…

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Perplexity has opened its Personal Computer feature to all Mac users through a new desktop app, bringing local AI agent capabilities beyond its previous Max subscriber waitlist. The tool extends Perplexity’s cloud-based Computer product onto users’ own devices, giving AI agents access to local files, native Mac applications, over 400 connectors, and the web to…

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